After a successfull Nightingale conference on 16 September, the project was ended 30 September 2021. Five years of hard work and intense cooperation between the five academic centers, as well as with industry and other interested, we are very satisfied with the resulting monitoring system of Checkpoint Cardio. Along the way we learned about the challenges and needs, enhanced by COVID-19, of remote wireless monitoring of patients. Technical and clinical challenges are still there and therefore the end of this project is not the end of our quest for smart monitoring and safer care. We hope to see you again in the future.